Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
Top Medical Research Studies
9
Eicosapentaenoic acid combats yeast biofilms
We set out to explore how eicosapentaenoic acid (EPA), a type of healthy fat, can disrupt the mature biofilms formed by a significant human fungal pathogen. These biofilms are important since they enhance the pathogen's ability to cause infections. Our investigation focused on the effects of a 1 mM EPA treatment on these established biofilms.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
Read More
8
EPA reduces yeast infection severity
We investigated how eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its health benefits, influences yeast infections, specifically those caused by Candida albicans. Using the Caenorhabditis elegans model, which provides a simpler system to study these interactions, we observed the effects of EPA supplementation on the nematode’s response to the fungal pathogen.
Our findings revealed that EPA not only altered lipid metabolism in these tiny worms but also significantly affected their survival during infection. Notably, we found that EPA inhibited the formation of hyphae—the structure that allows C. albicans to invade and damage host tissues—leading to a delay in the death of C. elegans. This effect seems to stem from a specific metabolite of EPA, called 17,18-epoxyeicosatetraenoic acid.
Furthermore, EPA prompted changes in gene expression related to biofilm formation in C. albicans, alongside stimulating the immune response in the worms. These results highlight a fascinating connection between dietary components like EPA and host defenses against infections, suggesting that incorporating omega-3 fatty acids could play a role in enhancing our resilience to such pathogens.
Our findings revealed that EPA not only altered lipid metabolism in these tiny worms but also significantly affected their survival during infection. Notably, we found that EPA inhibited the formation of hyphae—the structure that allows C. albicans to invade and damage host tissues—leading to a delay in the death of C. elegans. This effect seems to stem from a specific metabolite of EPA, called 17,18-epoxyeicosatetraenoic acid.
Furthermore, EPA prompted changes in gene expression related to biofilm formation in C. albicans, alongside stimulating the immune response in the worms. These results highlight a fascinating connection between dietary components like EPA and host defenses against infections, suggesting that incorporating omega-3 fatty acids could play a role in enhancing our resilience to such pathogens.
Read More
Most Useful Reviews
9
Promotes hair growth
Hair grows quite remarkably, almost like a yeast infection. I suggest giving it a try.
Read More
7.5
Facial hair support
The quality of the fish lacks flavour since I was 18, but the large packaging is beneficial. It aids in growing facial hair and provides good omega, which is advantageous for heart health, despite some issues with yeast infections.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
Eicosapentaenoic acid combats yeast biofilms
We set out to explore how eicosapentaenoic acid (EPA), a type of healthy fat, can disrupt the mature biofilms formed by a significant human fungal pathogen. These biofilms are important since they enhance the pathogen's ability to cause infections. Our investigation focused on the effects of a 1 mM EPA treatment on these established biofilms.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
Read More
8
EPA reduces yeast infection severity
We investigated how eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its health benefits, influences yeast infections, specifically those caused by Candida albicans. Using the Caenorhabditis elegans model, which provides a simpler system to study these interactions, we observed the effects of EPA supplementation on the nematode’s response to the fungal pathogen.
Our findings revealed that EPA not only altered lipid metabolism in these tiny worms but also significantly affected their survival during infection. Notably, we found that EPA inhibited the formation of hyphae—the structure that allows C. albicans to invade and damage host tissues—leading to a delay in the death of C. elegans. This effect seems to stem from a specific metabolite of EPA, called 17,18-epoxyeicosatetraenoic acid.
Furthermore, EPA prompted changes in gene expression related to biofilm formation in C. albicans, alongside stimulating the immune response in the worms. These results highlight a fascinating connection between dietary components like EPA and host defenses against infections, suggesting that incorporating omega-3 fatty acids could play a role in enhancing our resilience to such pathogens.
Our findings revealed that EPA not only altered lipid metabolism in these tiny worms but also significantly affected their survival during infection. Notably, we found that EPA inhibited the formation of hyphae—the structure that allows C. albicans to invade and damage host tissues—leading to a delay in the death of C. elegans. This effect seems to stem from a specific metabolite of EPA, called 17,18-epoxyeicosatetraenoic acid.
Furthermore, EPA prompted changes in gene expression related to biofilm formation in C. albicans, alongside stimulating the immune response in the worms. These results highlight a fascinating connection between dietary components like EPA and host defenses against infections, suggesting that incorporating omega-3 fatty acids could play a role in enhancing our resilience to such pathogens.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Promotes hair growth
Hair grows quite remarkably, almost like a yeast infection. I suggest giving it a try.
Read More
7.5
Facial hair support
The quality of the fish lacks flavour since I was 18, but the large packaging is beneficial. It aids in growing facial hair and provides good omega, which is advantageous for heart health, despite some issues with yeast infections.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Wang S, Xie S, Li T, Liu J, Wang P, et al. Eicosapentaenoic acid as an antibiofilm agent disrupts mature biofilms of . Biofilm. 2025;9:100251. doi:10.1016/j.bioflm.2024.100251
- Mokoena NZ, Steyn H, Hugo A, Dix-Peek T, Dickens C, et al. Eicosapentaenoic acid influences the pathogenesis of Candida albicans in Caenorhabditis elegans via inhibition of hyphal formation and stimulation of the host immune response. Med Microbiol Immunol. 2023;212:349. doi:10.1007/s00430-023-00777-6
